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. 2011 Jun 3;6(6):e20457. doi: 10.1371/journal.pone.0020457

Table 1. Association of MBP locus with rheumatoid arthritis in the Japanese population.

Chr dbSNPID Gene Allele DNA Collection Genotype counts Success rate HWEp RAF** p-value OR mhp ***
Ref.(A1)/Var.(A2) A1A1 A1A2 A2A2 (95%CI)
18q23 rs2000811 MBP C/T* 1 case 203 303 136 99.8 0.25 0.45 0.0036 1.25
control 344 442 148 100 0.76 0.4 (1.08–1.44)
2 case 95 152 79 99.7 0.24 0.48 5.7×10−4 1.49
control 120 131 46 100 0.31 0.38 (1.19–1.87)
3 case 283 392 182 98.1 0.034 0.44 0.023 1.17
control 298 404 134 97.8 0.88 0.4 (1.02–1.34)
4 case 393 622 233 98.7 0.63 0.44 0.0041 1.19
control 341 451 141 98.4 0.68 0.39 (1.06–1.35)
3+4 case 676 1014 415 98.5 0.32 0.44 3.0×10−4 1.18
control 639 855 275 98.1 0.69 0.4 (1.08–1.30)
pooled case 974 1469 630 98.9 0.078 0.44 4.0×10−8 1.23 2.7×10−8
control 1103 1428 469 98.9 0.85 0.39 (1.14–1.32)

*risk allele for the disease,

**risk allele frequency, and

***p-value in meta-analysis using Cochran-Mantel-Haenszel test.