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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Nat Neurosci. 2011 Feb 27;14(4):452–458. doi: 10.1038/nn.2778

Table 1.

Significant GO terms of the exons regulated by TDP-43.

GO term p-value referenc
e exons		 TDP-43 regulated exons
organ
morphogenesis		 <0.001 811 13 BCL2L11_E5, COL4A3BP_E12, CTNND1_E30,
DLC1_E2, FGFRL1_E4, FZD6_E2, MACF1_E68,
MEF2D_E11, PLEKHA1_E21, PLEKHA1_E23,
TFAP2A_E2, TLE1_E10, TPM1_E7
neural tube
closure		 0.001 45 3 DLC1_E2, FZD6_E2, TFAP2A_E2
homeostasis of
number of cells		 0.01 187 4 BCL2L11_E5, RPS24_E11, RPS24_E9, SOX6_E9
mitotic cell
cycle		 0.016 856 9 CLIP1_E33, HORMAD1_E4, KIF2A_E19,
MYO16_E8, PMF1_E2, PSMD6_E4, RBM38_E3,
SIRT7_E9, STAG2_E36
cell surface
receptor linked
signaling
pathway		 0.018 2005 16 ANXA1_E2, BRD8_E24, CNTFR_E2, CTNND1_E30,
FZD6_E2, GRM4_E7, HOMER2_E5, IRAK3_E2,
MACF1_E68, MADD_E40, PILRB_E25,
PLEKHA1_E21, PLEKHA1_E23, PTPRD_E78,
TLE1_E10, TNIK_E15
chordate
embryonic
development		 0.021 475 6 BCL2L11_E5, COL4A3BP_E12, DLC1_E2,
FZD6_E2, SOX6_E9, TFAP2A_E2
lipid transport 0.037 276 4 ANXA1_E2, ATP11C_E36, COL4A3BP_E12,
STARD4_E5