Table 2. Assessment of assay performance using P. falciparum samples obtained from patients with malaria (short-term and non-cultured samples).
Intensity (R>0.1) | Filtration Aa | Filtration Bb | Correlation between replicatesc | ||
Origin | No. samples | n° SNPs | n° SNPs | n° SNPs | |
PNG | 23 | 310 | 312 | 309 | 0.997 |
Thailand | 19 | 313 | 311 | 306 | 0.998 |
Cambodia | 22 | 299 | 310 | 295 | 0.996 |
Kenya | 19 | 310 | 305 | 304 | 0.998 |
Burkina Faso | 37 | 308 | 314 | 307 | 0.999 |
Mali | 23 | 311 | 313 | 307 | 0.999 |
Samples assessed on 319 “reliable” SNPs.
Filtration criteria A: SNPs with genotype concordance between replicates >0.95.
Filtration criteria B: SNPs with R>0.1 and with genotype concordance between replicates >0.95.
Mean correlation between replicates.