Table 1. Characteristics of the study population.

Variables	ADN = 275	VaDN = 119	ControlN = 423
Age (mean±SD)	78.2±8.0*	78.6±7.1*	71.4±7.4
Female (%)	180 (65)*	63 (53)	240 (57)
Education (%)≤6 years6–12years>12 years	139 (51)*95 (35)41 (15)	72 (59)*36 (30)14 (11)	43 (10)176 (42)204 (48)
BMI at age 40 s kg/m2(mean±SD)	22.4±3.2	24.1±2.9*	22.0±2.8
Cigarette smoking (%)	59 (22)*	35 (30)*	63 (15)
Alcohol consumption (%)	36 (13)	21 (18)*	42 (10)
DM (%)	49 (18)*	43 (36)*	52 (12)
Hypertension (%)	107 (39)*	78 (66)*	207 (49)
Hyperlipidemia (%)	49 (18)*	28 (24)	122 (29)
Cardiovascular disease (%)	63 (23)	38 (32)	119 (28)
APOE e4 carriers (%)	109 (40)*	25 (21)	61 (15)

*p<0.05 for comparing cases (AD and VaD) and controls.

Abbreviations: AD, Alzheimer's disease; VaD, vascular dementia; BMI, body mass index; DM, diabetes mellitus; APOE e4, apolipoprotein E e4.