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. 2011 Jun 6;6(6):e20729. doi: 10.1371/journal.pone.0020729

Figure 1. FBA-TPQ preferentially decreases cell viability and growth of A2780 and OVCAR-3 cells but not normal IOSE-144 cells.

Figure 1

A, Chemical structure and molecular formula of FBA-TPQ; B, Cell viability (MTS) assay of human ovarian carcinoma cells (A2780 and OVCAR-3) and nontumorigenic OSE cells (IOSE144) after a 48 h incubation with FBA-TPQ; C&D&E, Cell growth inhibition after 0, 24, 48 or 72 h exposure of A2780 (C), OVCAR-3 (D) and IOSE-144 (E) cells to FBA-TPQ(at concentrations of 0, 0.5, 0.75 and 1.0 µM). All values are representative of at least three independent experiments with similar results, and are presented as the percentage of cell growth inhibition, where vehicle-treated cells were regarded as 100% viable (0% growth inhibition).