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A, Superoxide, B, DCFDA-induced flurorescence levels and C, NADPH-oxidase activity was increased in diabetic arteries which was reduced with DiOHF treatment. A, Superoxide levels in diabetic arteries were attenuated by the presence of L-NNA (100 µM), indicating eNOS uncoupling. n = 9–10 experiments. * p<0.05, ** p<0.01, *** p<0.001.
