Table 1. Mean body weight gained, blood glucose and glycated haemoglobin levels at the end of the experiment of normal and diabetic rats with or without 3′, 4′-dihydroxyflavonol (DiOHF, 1 mg/kg s.c. daily for 7 days) treatment.
8 weeks after vehicle or STZ treatment | ||||||||
n | Normal | n | Normal+DiOHF | n | Diabetic | n | Diabetic+DiOHF | |
Body weight gained (g) | 22 | 307±12 | 19 | 286±5 | 19 | 126±10* | 20 | 177±10† ‡ |
Blood glucose (mM) | 22 | 8.3±0.6 | 19 | 7.3±0.6 | 19 | 32.4±0.3* | 20 | 30.2±0.9‡ |
HbA1c (%) | 8 | 6.1±0.2 | 7 | 5.8±0.2 | 10 | 13.5±0.5* | 10 | 12.6±0.6‡ |
n = the number of rats. * Significantly different from normal group (Bonferroni's test, p<0.05), † Significantly different to diabetic group, p<0.05, Bonferroni's test. ‡ Significantly different to Normal+DiOHF group, p<0.05, Bonferroni's test. Results are shown as mean±SEM.