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. 2011 Jun 6;6(6):e20848. doi: 10.1371/journal.pone.0020848

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Bess et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Expression of IκB in (A) pulmonary endothelial cells from AMPKα2^+/+ and AMPKα2^-/- mice, and (B) in COS-7 cells expressing either constitutively active (CA) or dominant negative (DN) AMPKα2. (C) IκB phosphorylation in CA- or DN-AMPKα2 expressing COS-7 cells and stimulated with solvent (Sol) or TNF-α (10 ng/mL). Data are expressed relative to values obtained in control virus-infected cells. The bar graphs summarize the results of 4 to 5 independent experiments; *P<0.05 versus CA or ^+/+.