Figure 2. External morphology and longevity in AD flies.
A) elav; +; + heterozygous fly one day after eclosion showing no defects on ventral proboscis, ventral abdomen, or in wings. B) Arrows indicate regions of the elav; APP; BACE heterozygous fly one day after eclosion showing melanotic masses on ventral proboscis, ventral abdomen, and curled wings. C) Quantification of the external defects shown in (B). n>50 in each case. Genotypes and treatments indicated. * indicates p<.001 between DMSO and L-685,458.