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. 2011 Jun 6;6(6):e20965. doi: 10.1371/journal.pone.0020965

Table 1. Mutation sequence of potential STAT3 binding sites.

Potential binding site 1 (-330∼-322) Potential binding site 2 (+64∼+72)
Wide type AATTTCCCTTAACTA TCTTTCCACTAAAGT
STAT3M1 AATCGCCCTTGACTA
STAT3M2 TCTCGCCACTGAAGT
Consensus sequence 5’-TTMXXXDMA-3’, where D is A, G, or T and M is A or C.

In bold is the consensus SIE motif, and the bold underlined letters correspond to the mutated bases from the SIE motif.