Table 4.
Mean Copy Numbers in AMD Patients and Controls
| Genes | Unadjusted |
Age-Adjusted |
||||
|---|---|---|---|---|---|---|
| Control | AMD | P | Control | AMD | P | |
| CCR3 | 2.00 ± 0.39 | 1.99 ± 0.42 | 0.86 | 1.96 (1.87–2.06) | 2.02 (1.93–2.11) | 0.42 |
| CFH | 2.04 ± 0.37 | 2.10 ± 0.34 | 0.24 | 2.01 (1.92–2.09) | 2.13 (2.05–2.21) | 0.05* |
| CX3CR1 | 2.23 ± 0.47 | 2.12 ± 0.41 | 0.05* | 2.23 (2.13–2.32) | 2.12 (2.04–2.20) | 0.10 |
| ERCC6 | 1.99 ± 0.11 | 1.98 ± 0.15 | 0.63 | 1.99 (1.95–2.02) | 1.98 (1.95–2.01) | 0.75 |
| HTRA1 | 2.08 ± 0.27 | 2.07 ± 0.25 | 0.86 | 2.05 (1.99–2.11) | 2.09 (2.03–2.15) | 0.36 |
| VEGF | 2.04 ± 0.19 | 2.00 ± 0.00 | 0.07 | 2.02 (1.99–2.05) | 2.01 (1.98–2.04) | 0.69 |
| GSTM1 | 0.91 ± 1.13 | 0.98 ± 1.12 | 0.71 | 0.89 (0.62–1.16) | 1.00 (0.74–1.26) | 0.60 |
| GSTT1 | 1.10 ± 0.74 | 1.28 ± 0.84 | 0.15 | 1.10 (0.90–1.29) | 1.28 (1.10–1.47) | 0.20 |
Data are presented as mean ± SD in the unadjusted results and as mean (95% CI) in the age-adjusted results. Unadjusted P values were calculated using the t-test, and age-adjusted P values were calculated using analysis of covariance.
P = 0.05.