Figure 6.
Effect of inhibition of P2X1 receptors on ATP-stimulated [Ca2+]i. Acini containing fura-2 were preincubated with NF023 (10−6–10−4 M) before stimulation with ATP (10−6 M). Trace shown in (A) represents the mean of three animals. Peak [Ca2+]i was calculated from three animals (B). Acini were preincubated with NF023 (10−6–10−4 M) before stimulation with ATP (10−6 M). Peroxidase secretion was measured from three animals (C). Data are mean ± SEM. *Statistical significance from basal (0). Arrow: addition of ATP.