Figure 2.
Effect of simultaneous addition of carbachol and BzATP on [Ca2+]i in lacrimal gland acini. Time-dependent increase in [Ca2+]i induced by the stimulation of lacrimal gland acini with cholinergic agonist carbachol (Cch), BzATP, or the two added simultaneously. The calculated [Ca2+]i response of the two agonists added simultaneously is also shown. Traces from seven experiments (A, C). Mean change in peak [Ca2+]i from seven experiments (B, D). Values are mean ± SEM. Arrows: time of agonist addition. *Significant difference from no additions (0). #Significant difference in experimental additivity from calculated additivity. n.s., no significant difference.