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. 2011 May 20;52(6):3381–3390. doi: 10.1167/iovs.11-7210

Figure 7.

Figure 7.

Effect of constitutively active PKCα or dominant-negative PKCα or PKCε on [Ca2+]i stimulated by BzATP in lacrimal gland acini. Time-dependent increase in [Ca2+]i induced by stimulation of lacrimal gland acini with BzATP (10−4 M; arrow) after 24-hour preincubation with control adenovirus-producing GFP (AdV-GFP), adenovirus-producing constitutively active PKCα (AdV-myrPKCα), or adenovirus-producing dominant-negative PKCα or PKCε (AdV- DNPKCα and AdV-DNPKCε, respectively). Traces from three experiments (A). Mean change in peak [Ca2+]i from three experiments (B). Values are mean ± SEM. Arrow: time of carbachol addition. *Significant difference from no addition. n.s., no significant difference.