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. 2011 May 26;52(6):3557–3566. doi: 10.1167/iovs.10-6358

Figure 1.

Figure 1.

Early-onset, slow progression of cone dysfunction in CNGB3−/− mice. Photopic and scotopic ERG recordings were performed in CNGB3−/− and WT mice at various ages from P15 to 18 months. (A, C, D) Photopic b-wave (A), scotopic a-wave (C), and scotopic b-wave (D) amplitudes in CNGB3−/− and WT mice. Data represent mean ± SD (n = 5–12 mice for each group). One-way ANOVA (Newman-Keuls) analysis was used to determine significance among different ages (*P < 0.05 compared with the value of CNGB3−/− mice at 1 month; XP < 0.05 compared with the value of WT mice at 1 month). (B, E) Representative photopic (B) and scotopic (E) ERG traces in CNGB3−/− and WT mice at 1, 6, and 12 months.