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. 2011 May 31;52(6):3825–3831. doi: 10.1167/iovs.10-6797

Figure 3.

Figure 3.

Decreases in caspase activation after treatment with edaravone 24 hours after RD creation. Activity of caspase-3 (A), -8 (B), and -9 (C) in AR, RD, and RD treated with 5 mg/kg edaravone. RD induced activation of caspase-8, -9, and -3, 1 day after RD, and treatment with 5 mg/kg edaravone significantly suppressed activation of these caspases. Data are expressed as the mean ± SE, n = 6. *P < 0.05, **P < 0.01.