Table 1.
Characteristics of hand vein subjects: Demographic, physical, and physiological. The left side of the table is for all subjects together. No differences were noted between pre- and post-study vital signs (P > 0.05). The right side shows the male and female subjects separately with standard errors. The P value reflects differences between the sexes
Baseline characteristics | Mean N = 18 | SEM | Males N = 11 | Females N = 7 | P Value |
---|---|---|---|---|---|
Age (years) | 33.2 | 2.8 | 30.5 ± 3.6 | 37.4 ± 4.6 | 0.25 |
Weight (kg) | 74.3 | 3.8 | 81.8 ± 4.5 | 62.6 ± 3.8 | 0.008 |
Height (m) | 1.7 | 0.03 | 1.77 ± 0.02 | 1.61 ± 0.02 | <0.001 |
BMI (kg/m2) | 25.1 | 0.86 | 25.8 ± 1.1 | 24.1 ± 1.4 | 0.35 |
Baseline dorsal hand vein diameter (mm) | 0.73 | 0.07 | 0.84 ± 0.1 | 0.55 ± 0.03 | 0.043 |
Dose of phenylephrine required for vasoconstriction to ~70% (ng/min) | 1620 | 460 | 1900 ± 700 | 1171 ± 470 | 0.46 |
Hand vein constriction with phenylephrine (%) | 69.3 | 3.4 | 68.6 ± 5.0 | 70.3 ± 4.3 | 0.82 |
Dose phenylephrine/percent hand vein constriction (ng/min/percent constriction) | 21.8 | 6.2 | 26.0 ± 9.4 | 15.3 ± 6.0 | 0.42 |
% | % | % | |||
Ethnicity | 0.81 | ||||
White | 50 | 54.5 | 42.9 | ||
Black | 5.6 | 0 | 14.3 | ||
East Asian | 33.3 | 36.4 | 28.6 | ||
South Asian | 11.1 | 9.1 | 14.3 | ||
Family history of hypertension | 0.011 | ||||
Yes | 22.2 | 0 | 57.1 | ||
No | 44.4 | 54.5 | 28.6 | ||
Unknown/indeterminate | 33.3 | 45.5 | 14.3 | ||
Non-smokers | 100 | 100 | 100 | ||
Prestudy vital signs | Mean | SEM | |||
Systolic blood pressure (mmHg) | 121.4 | 2.3 | 123.8 ± 3.7 | 115.4 ± 5.5 | 0.21 |
Diastolic blood pressure (mmHg) | 76.1 | 1.6 | 72.1 ± 3.2 | 71.9 ± 4.7 | 0.97 |
Pulse (beats/minute) | 72.1 | 1.9 | 67.6 ± 2.2 | 72.7 ± 4.8 | 0.30 |
Post-study vital signs | Mean | SEM | |||
Systolic blood pressure (mmHg) | 122.4 | 2.8 | 122.7 ± 2.2 | 117.4 ± 6.1 | 0.37 |
Diastolic blood pressure (mmHg) | 78.5 | 1.6 | 77.6 ± 2.4 | 76.1 ± 3.9 | 0.74 |
Pulse (beats/minute) | 72.1 | 1.8 | 68.6 ± 0.15 | 72.0 ± 2.4 | 0.39 |