(A) Exposure to both hydrocortisone (left) and betamethasone (right) on gestational day 15 significantly decreased postnatal weight on P15; *p<0.05.
(B) In different groups of prenatally exposed rats, hydrocortisone (HC) again decreased postnatal body weight. When canrenoic acid (CAN; an mineralocorticoid receptor antagonists) was co-administered with hydrocortisone, the weight loss was further amplified. Canrenoic acid applied in control arrangement had no such effect on the body weight; *p<0.05 versus 2x saline + 2x saline group or 2x CAN + 2x saline group; #p<0.05 versus 2x saline + 2x HC group.