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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Epilepsy Res. 2011 Mar 22;95(1-2):9–19. doi: 10.1016/j.eplepsyres.2011.01.019

Figure 1. Prenatal corticosteroid exposure decreases postnatal weight.

Figure 1

(A) Exposure to both hydrocortisone (left) and betamethasone (right) on gestational day 15 significantly decreased postnatal weight on P15; *p<0.05.

(B) In different groups of prenatally exposed rats, hydrocortisone (HC) again decreased postnatal body weight. When canrenoic acid (CAN; an mineralocorticoid receptor antagonists) was co-administered with hydrocortisone, the weight loss was further amplified. Canrenoic acid applied in control arrangement had no such effect on the body weight; *p<0.05 versus 2x saline + 2x saline group or 2x CAN + 2x saline group; #p<0.05 versus 2x saline + 2x HC group.