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. Author manuscript; available in PMC: 2012 Jun 6.
Published in final edited form as: Mol Pharm. 2011 Apr 21;8(3):767–773. doi: 10.1021/mp100382m

Fig 4.

Fig 4

Coronal slices at the same level before (left panels) and after (right panels) removal of internal organs. One representative animal for each of the three groups (left to right): transplanted with islets, betalox5 cells, and HEK293 cells, all pretargeted with MORF-HPi1 and receiving 99mTc-cMORF 48 h later. The presence of a focal radioactivity accumulation in the human islet and betalox5 transplanted mice but not in the HEK293 transplanted mice and the continuing presence of signal after the removal of internal organs confirms that the accumulations are at the site of transplantation and are the result of specific binding of the antibody to the target.