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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Chromatogr A. 2011 May 13;1218(26):4059–4064. doi: 10.1016/j.chroma.2011.05.006

Figure 4. Ca2+-dependence of IAPP, glucagon, and insulin secretion.

Figure 4

Insulin, IAPP, and glucagon secretion was measured from 15 islets in 4 mM glucose with 0 mM extracellular Ca2+ (light grey bars), 4 mM glucose with 2.4 mM extracellular Ca2+ (black bars), 20 mM glucose with 0 mM extracellular Ca2+ (white bars), and 20 mM glucose with 2.4 mM extracellular Ca2+ (dark grey bars). Average values of four replicate experiments are given with the error bars corresponding to +/− 1 standard error of the mean. IAPP and glucagon values are shown on the left y-axis and insulin values are shown on the right y-axis.