Skip to main content
. Author manuscript; available in PMC: 2012 Apr 30.
Published in final edited form as: Adv Drug Deliv Rev. 2011 Mar 1;63(4-5):324–330. doi: 10.1016/j.addr.2011.01.013

Figure 1.

Figure 1

Differentiated somatic cells (fibroblasts) can be reprogrammed into induced pluripotent stem cells (iPSC) with retroviral over-expression of the four factors Oct4, Sox2, Klf4, c-Myc. iPSC have the potential to differentiate into all somatic cell types.