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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Neurotoxicology. 2011 Apr 14;32(4):471–477. doi: 10.1016/j.neuro.2011.03.013

Fig. 2.

Fig. 2

Treatment of PC6-3 cell lysate with varying concentrations of DOPAL leads to TH inhibition and a decrease in L-DOPA production. (A) L-DOPA production over 2 h shows significant inhibition by DOPAL. (B) Enhancement of 2A DOPAL treatment experiments. (C) Comparison of initial linear slopes shows the concentration-dependent decrease in L-DOPA production. Values shown represent the mean ± SEMs (n = 4). **Significantly different from the control (p < 0.05). In all graphs: (●) control, (--) 0.1 μM DOPAL, (□) 0.5 μM DOPAL, (▲) 1.0 μM DOPAL, (◇) 2.5 μM DOPAL, (◆) 5.0 μM DOPAL, (○) 10.0 μM DOPAL.