Table 1.
Variable | Era I: 1988–1999 (n = 1,631) | Era II: 2000–2006 (n = 5,237) | P value |
---|---|---|---|
Age, years | |||
≤56 | 910 | 2,592 | <0.001 |
>56 | 721 | 2,645 | |
Sex | |||
Male | 1,045 | 3,324 | =0.66 |
Female | 586 | 1,913 | |
Breslow depth, mm | |||
0 | 38 | 109 | <0.001 |
≤1 | 233 | 897 | |
1.01–2 | 299 | 1,261 | |
2.01–4 | 411 | 1,327 | |
>4 | 315 | 1,072 | |
Unknown | 335 | 571 | |
Ulceration | |||
Absent | 1,378 | 3,682 | <0.001 |
Present | 253 | 1555 | |
Number of lymph node metastases | |||
1 | 886 | 3,225 | <0.001 |
2–3 | 377 | 1,355 | |
≥4 | 234 | 532 | |
Unknown | 134 | 125 | |
Surgery | |||
Amputation | 2 | 89 | <0.001 |
Ablation | 1 | 2 | |
Local excision | 50 | 1054 | |
Wide excision (1–2 cm) | 427 | 3,555 | |
Wide excision (>2 cm) | 0 | 264 | |
None | 27 | 246 | |
Unknown | 1,124 | 29 |