Figure 3.

Infectious progeny of C. trachomatis samples cultured with iron-chelating agents. Various concentrations of DFO (black bars) or Bpdl (white bars) were included in the culture medium added immediately post-chlamydial invasion. Infectious titers were quantified after 24 h of treatment and presented as inclusion forming units (IFU) per milliliter of inoculum (y-axis). Graph represents the mean ± SD derived from at least two independent experiments, assayed in triplicate. Statistical significance determined with unpaired, two-tailed t-test in conjunction with F-test (*p < 0.05, **p < 0.01, ***p < 0.001). Asterisks without brackets represent comparison to the untreated control; brackets indicate the comparison of DFO to Bpdl at the same concentration.