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Prevalence of genetic and epigenetic alteration in the different subtypes of serrated polyps by combining all comparable data from [73, 75–84].
| Polyp type | BRAF mutation | KRAS mutation | CIMP-H* | MLH1 methylation | MGMT methylation |
|---|---|---|---|---|---|
| HP | |||||
| Microvesicular | 66.3% | 12.3% | 47.4% | 39.5% | 26.3% |
| Goblet-cell | 20% | 48.4% | 14.3% | 14.3% | 0% |
| All subtypes | 51.5% | 22.1% | 38.5% | 27% | 14.8% |
| SSA/P | 83.9% | 5.8% | 75.9% | 42.6% | 25% |
| TSA | 62.5% | 22.4% | 79.3% | 47.5% | 74.2% |
