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. Author manuscript; available in PMC: 2011 Jun 7.
Published in final edited form as: Stem Cells. 2009 Nov;27(11):2703–2711. doi: 10.1002/stem.229

Figure 3.

Figure 3

Overexpression of mouse V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (Mafa) and pancreatic and duodenal homeobox factor 1 (Pdx1) activates an ectopic insulin promoter construct in human islet-derived precursor cells (hIPCs). Fluorescence profiles of hIPCs infected with 100 multiplicity of infection each of (A) adenoviruses expressing mouse Mafa (Ad-Mafa) and mouse Pdx1 (Ad-Pdx1); (B) adenovirus expressing rat insulin promoter/green fluorescent protein (Ad-RIP/GFP); (C) Ad-GFP, Ad-Mafa, and Ad-Pdx1; and (D) Ad-RIP/GFP, Ad-Mafa, and Ad-Pdx1. Cells were collected for cytometric analysis 3 days after infection. Data are representative of two experiments. Adenovirus expressing neurogenic differentiation 1 was not included in these experiments because this adenovirus construct coexpresses GFP. Abbreviations: FL1-H, peak height of fluorescent detector 1 signal.