Skip to main content
. Author manuscript; available in PMC: 2011 Jun 7.
Published in final edited form as: J Med Chem. 2009 Dec 10;52(23):7580–7592. doi: 10.1021/jm900426g

Figure 1.

Figure 1

Inhibition of radioligand binding by (N)-methanocarba nucleoside analogues in membranes of CHO cells expressing the human A3AR. Inhibition curves are shown for the agonist analogues containing a 5′-N-methyluronamide group and compounds 15 (amine functionalized congener), 17b (biotinylated probe), and 18 (fluoresecent probe) and for the truncated partial agonist 22. All of the analogues shown were highly selective for the A3AR in comparison to the A1 and A2aARs.