Distinctive facial features include fullness to the upper eyelid, mild telecanthus, small ears with hypoplastic superior crus and ear lobes, short nose with broad nasal bridge, bulbous nasal tip, flared alae nasi, tented upper lip, down-turned corners of the mouth, and micrognathia. Patients’ facial features shown from youngest age (17 months) to oldest age (24 years). A. Patient 4, B. Patient 1, C. Patient 5, D. Patient 2, E. Patient 6, F. Patient 9, G. Patient 3, H. Patient 7, I. Patient 8.