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Images showing pharmacokinetic modelling parameters. (a-c) Malignant tumour within the breast illustrated on dynamic contrast-enhanced MRI and using the vascular parameters: (a) transfer constant (Ktrans); (b) extravascular extracellular space (ve); (c) rate constant from extravascular/extracellular space back into plasma (kep). All these parameters are higher at the tumour periphery compared to the centre and in the satellite nodule, indicative of more neoangiogenesis in these areas.
