Table 1.
Distribution of immunoscoring for hypoxia pathway factors and cut-off values used in semiquantitative analyses
| Factor | n (%) |
|---|---|
| Hypoxia-inducible factor-1α | |
| 0 | 33 (19.3%) |
| 1 | 100 (58.5%) |
| 2 | 38 (22.2%) |
| Missing | 16 |
| Vascular endothelial growth factor | |
| 0 | 32 (20.0%) |
| 1 | 39 (24.4%) |
| 2 | 37 (23.1%) |
| 4 | 52 (32.5%) |
| Missing | 27 |
| Carbonic anhydrase IX | |
| 0 | 125 (75.3%) |
| 1 | 20 (12.1%) |
| ≥2 | 21 (12.6%) |
| Missing | 21 |
| Prolyl hydroxylase 1 | |
| 0 | 129 (73.3%) |
| 1 | 43 (24.4%) |
| 2 | 3 (1.7%) |
| 3 | 1 (0.6%) |
| Missing | 11 |
| Prolyl hydroxylase 2 | |
| 0 | 78 (47.8%) |
| 1 | 51 (31.3%) |
| 2 | 30 (18.4%) |
| 3 | 4 (2.4%) |
| Missing | 24 |
| Prolyl hydroxylase 3 | |
| 0 | 108 (61.0%) |
| 1 | 53 (29.9%) |
| 2 | 15 (8.5%) |
| 3 | 1 (0.6%) |
| Missing | 10 |
Data refer to the number of tumours positive in each intensity score category.