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Analysis of the immune responses induced by vaccination with anti-Id scFv69. IgG1, IgG2a and IgG2b isotype distribution of anti-scFv69 (A) and anti-HER2 (B) antibodies in sera from MMTV.f.huHER2(Fo5) transgenic mice immunized with PBS (upper panels) or scFv69 (lower panels); (C) IgG1/IgG2a ratio of the anti-scFv69 or anti-HER2 response in transgenic mice immunized with PBS or scFv69.
