Table 4. IFN-γ response up-regulated genes involved in the host defense pathways.
| Category | # genes in category | Percentage |
|---|---|---|
| Class I pathway and accessory molecules | 32 | 18% |
| Class II pathway and accessory molecules | 13 | 8% |
| Cytokine network | 24 | 14% |
| Apoptosis-related genes | 17 | 10% |
| Transcription factors | 10 | 6% |
| Chemokines | 10 | 6% |
| GTP-binding proteins (p47 GTPase family) | 10 | 6% |
| HIN-200 gene family | 7 | 4% |
| Antiviral actions | 7 | 4% |
| Complement and Fc receptors | 6 | 3% |
| Tryptophan metabolism | 5 | 3% |
| Nitric oxide and respiratory burst | 2 | 1% |
| Cellular adhesion molecules | 2 | 1% |
| Other immune functions | 27 | 16% |