Skip to main content
. Author manuscript; available in PMC: 2011 Jun 7.
Published in final edited form as: Folia Parasitol (Praha). 2005 May;52(1-2):182–192. doi: 10.14411/fp.2005.023

Fig. 2.

Fig. 2

Alignment (Clustal_W) of full-length microsporidian methionine aminopeptidase type 2 with human methionine aminopeptidase type 2. Microsporidia: Encephalitozoon cuniculi (AF440270), E. intestinalis (AY224693), and E. hellem (AY224694); human: Homo sapiens (NP006829). The amino acids D-D-H-E-E indicated by bold text are involved in binding the two metal ions required for the catalytic site. The locations of primers M1 through M4 are indicated by underlined text. The shaded residue is the histidine where the spiro-epoxide of fumagillin is predicted to form a covalent bond with MetAP2.