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. 2011 Feb 10;117(20):5494–5502. doi: 10.1182/blood-2010-11-319483

Table 1.

Embryonic lethality of due to deletion of Mfrn1

Embryos/pups ≤ E9.5 (n = 37) ≥ E11.5 (n = 41) Newborn (n = 64)
Mfrn1+/+ 10 10 20
Mfrn1+/− 19 22 44
Mfrn1−/− 8 0 0
Not determined (necrotic embryos) 0 9 0

Mice (Mfrn1+/−) heterozygous for a Mfrn1 deletion were intercrossed and the progeny were genotyped.