Men |
Children |
Nosocomial infection |
Women |
Known lesion on prior diagnosis |
Functional or structural urinary tract anomaly |
Obstruction (e.g., stone, ureteropelvic junction obstruction) |
Pregnancy |
Diabetes |
Spinal cord injury |
Neurological disorders (e.g., multiple sclerosis) that affects bladder function |
Indwelling catheter |
Comorbidities that predispose to papillary necrosis (e.g., sickle cell disease, severe diabetes, analgesic abuse, Pseudomonas species infection) |
Infection with an unusual organism (e.g., tuberculosis) |
Suspected lesion based on history |
Unresolved urinary tract infections – failed response to antimicrobial therapy |
Bacterial persistence (recurrent urinary tract infections with the same organism) |
Infection with urea-splitting organisms |
Recurrent febrile urinary tract infections in childhood |
Suspected lesion based on symptoms |
Febrile urinary tract infections (especially >3 days) |
Renal colic |
Gross hematuria |