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. 1999 Dec;9(12):1294–1304. doi: 10.1101/gr.9.12.1294

Table 3.

Quantiles of FR and CDR Mutability and CDR/FR Mutability Ratio of the Real Sequence Sets Compared to Translationally Equivalent Variants in Various Species

Species Serine included Serine excluded



μF μC μCF μF μC μCF






Human VH 0.006 0.957 0.998 0.002 0.57 0.744
Sheep Vλ 0.001 0.976 1 0.001 0.14 0.687
Rainbow trout VH 0.1 0.983 0.994 0.007 0.325 0.805
Horned Shark VH 0.047 0.675 0.974 0.022 0.787 0.983
African toad VH 0.423 0.991 0.985 0.499 0.561 0.546