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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Magn Reson. 2011 Jan 21;209(2):195–206. doi: 10.1016/j.jmr.2011.01.008

Figure 1.

Figure 1

Spectral representations of numerical simulations that illustrate the method of dipolar coupling correlated isotropic chemical shift analysis described in the text. A., C., and E. are spectra from “flipped samples” with their bilayer normals parallel to the magnetic field. B., D., and F. are spectra from standard samples with their bilayer normals perpendicular to the magnetic field. A. and B. are SLF spectra simulated for an ideal 10-residue helix, where all amide sites have the same isotropic chemical shift. C. and D. are SLF spectra for the same helix with randomized chemical shift tensors as described in the text. The isotropic value of the heteronuclear dipolar coupling is zero. E. and F. are HETCOR spectra that can be correlated to the SLF spectra through the 15N chemical shift frequencies. G. Is the spectral representation of the 15N and 1H isotropic chemical shift values calculated from the two HETCOR spectra.