Figure 7.
D1-like receptor antagonist-mediated blockade of galanin-induced ERK1/2 phosphorylation in rat hippocampal slices. Slices from dorsal (black) or ventral (white) hippocampus were treated for 10 min with medium, SCH 23390 (10 μm), or M40 (10 μm) before the addition of galanin (300 nm) and an additional incubation period of 10 min. The inmunoreactive bands from four slices from two different animals were quantified and the values represent the mean ± SEM of the percentage of phosphorylation relative to the basal levels found in untreated slices (100%). *p < 0.05; **p < 0.01 (significantly different compared to the effect of galanin alone; one-way ANOVA with Bonferroni's correction).