Table 1.
Baseline characteristics of the trial population
| Median (IQR) |
P Values for the Difference | ||
|---|---|---|---|
| Experimental Intervention (n = 238) | Standard Care Control (n = 236) | ||
| Age (years) | 67 (62, 72) | 67 (61, 72) | 0.85 |
| Baseline serum creatinine (μmol/L) | 127 (112, 145) | 128 (114, 143) | 0.85 |
| Baseline eGFR (ml/min per 1.73 m2) | 42 (40, 46) | 42 (37, 46) | 0.78 |
| Weight (kg) | 83 (72, 96) | 82 (72, 91) | 0.33 |
| Systolic BP | 128 (116, 140) | 132 (120, 144) | 0.001 |
| Diastolic BP | 74 (66, 80) | 74 (68, 81) | 0.96 |
| Proteinuria (g/day) | 0.11 (0.07, 0.2) | 0.12 (0.08, 0.22) | 0.06 |
| LDL cholesterol (mmol/L) | 2.6 (2.1, 3.3) | 2.7 (2.1, 3.5) | 0.07 |
| Hba1c among diabetics (%) | 6.9 (6.4, 7.9) | 7.1 (6.3, 7.6) | 0.58 |
| Hemoglobin (g/L) | 136 (125, 144) | 134 (126, 144) | 0.33 |
| Number (%) | Number (%) | ||
| Female | 131 (55) | 132 (56) | 0.85 |
| Caucasian | 223 (94) | 224 (95) | 0.28 |
| Retired | 144 (61) | 158 (67) | 0.15 |
| Working | 58 (24) | 55 (23) | 0.42 |
| Post-secondary school education | 96 (40) | 100 (42) | 0.90 |
| Married/living as married | 167 (70) | 154 (65) | 0.37 |
| Living in own home, no hired assistance | 224 (94) | 219 (93) | 0.77 |
| Current smoker | 18 (8) | 18 (8) | 1.0 |
| Systolic BP >130 mmHg | 84 (36) | 120 (51) | 0.001 |
| Systolic BP >140 mmHg | 61 (26) | 81 (35) | 0.05 |
| Diastolic BP >80 mmHg | 40 (17) | 60 (26) | 0.03 |
| Diastolic BP >90 mmHg | 10 (4) | 11 (5) | 0.98 |
| Diabetes mellitus | 73 (31) | 76 (33) | 0.65 |
| Angina | 19 (8) | 28 (12) | 0.21 |
| History of myocardial infarction | 39 (17) | 33 (14) | 0.55 |
| History of PTCA | 26 (11) | 20 (9) | 0.46 |
| History of CABG | 25 (11) | 19 (8) | 0.45 |
| History of heart failure | 13 (6) | 9 (4) | 0.53 |
| History of cardiac arrhythmia | 32 (14) | 32 (14) | 1.0 |
| History of cerebrovascular event | 10 (4) | 15 (7) | 0.40 |
| History of hypertension | 182 (78) | 178 (77) | 0.87 |
| History of chronic lung disease | 46 (20) | 49 (21) | 0.78 |
| History of cancer | 34 (15) | 40 (17) | 0.50 |
| Taking an ACE inhibitor or ARB | 165 (70) | 156 (66) | 0.51 |
| Taking a statin | 118 (25) | 103 (22) | 0.23 |
PTCA, percutaneous transluminal coronary angioplast; CABG, coronary artery bypass graft; ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker. Continuous variables are presented as medians (intraquartile range). Binary variables are presented as numbers (percentages).