Table 3.
Baseline and change in leukocyte count of the study participants by CKD
| Clinical Characteristic | Non-CKD Intercept | No CKD Slope/yr | CKD Intercept | CKD Slope/yr | Difference in Intercept (CKD − no CKD) | P for Difference in Intercept | Difference in Slope (CKD − no CKD) | P for Difference in Slopes |
|---|---|---|---|---|---|---|---|---|
| Leukocytes (K/μl) | 7.7 ± 0.25 | 0.05 ± 0.05 | 7.6 ± 0.16 | 0.04 ± 0.03 | −0.1 (−0.7, 0.5) | >0.1 | −0.01 (−0.13, 0.10) | >0.1 |
| Absolute granulocyte count | 5226 ± 199 | 2 ± 38 | 4947 ± 120 | 70 ± 26a | −279 (−735, 177) | >0.1 | 68 (−23, 159) | >0.1 |
| Absolute eosinophil count | 192 ± 14 | −1 ± 2 | 225 ± 9 | −6 ± 1a | 34 (2, 65) | 0.04 | −5 (−10, 0) | 0.06 |
| Granulocytes (%) | 63.0 ± 0.87 | 0.39 ± 0.19a | 65.3 ± 0.54 | 0.52 ± 0.13a | 2.3 (0.3, 4.3) | 0.02 | 0.13 (−0.32, 0.58) | >0.1 |
| Lymphocytes (%) | 26.1 ± 0.75 | −0.43 ± 0.16a | 23.0 ± 0.47 | −0.55 ± 0.11a | −3.1 (−4.8, −1.3) | <0.001 | −0.12 (−0.50, 0.26) | >0.1 |
| Monocytes (%) | 7.9 ± 0.21 | 0.03 ± 0.04 | 8.0 ± 0.13 | 0.07 ± 0.02a | 0.1 (−0.4, 0.6) | >0.1 | 0.03 (−0.05, 0.12) | >0.1 |
| Eosinophils (%) | 2.6 ± 0.19 | −0.01 ± 0.03 | 3.2 ± 0.12 | −0.07 ± 0.02a | 0.6 (0.2, 1.0) | <0.01 | −0.06 (−0.14, 0.01) | 0.1 |
| Basophils (%) | 1.6 ± 0.28 | −0.08 ± 0.05 | 1.6 ± 0.16 | −0.04 ± 0.03 | −0.0 (−0.7, 0.6) | >0.1 | 0.04 (−0.06, 0.15) | >0.1 |
± denotes standard error, number in parenthesis reflect 95% confidence intervals of the mean.
a
Slope is significantly different from zero.