Table 1.
Baseline characteristics by level of kidney function using the CKD-Epi equation
| Characteristics | Total | eGFREPI (ml/min per 1.73 m2) |
Pa | ||
|---|---|---|---|---|---|
| >60 | 30 to 59 | <30 | |||
| n | 1028 | 501 | 477 | 50 | |
| Age | 85.5 (3.5) | 85.2 (3.4) | 85.7 (3.6) | 86.2 (3.7) | <0.01 |
| Women | 63.8 | 62.7 | 66.5 | 50.0 | 0.89 |
| White race | 85.9 | 83.2 | 88.5 | 88.0 | 0.03 |
| Body mass index (kg/m2) | 26.8 (4.7) | 26.6 (4.6) | 26.8 (4.7) | 27.8 (5.0) | 0.22 |
| Ever smoked | 49.2 | 50.2 | 48.2 | 48.0 | 0.54 |
| Diabetes | 14.4 | 13.1 | 13.9 | 32.0 | 0.02 |
| Hypertension | 65.6 | 60 | 69.5 | 84.0 | <0.01 |
| Systolic blood pressure (mmHg) | 132.7 (21.1) | 133.7 (20.8) | 131.4 (20.9) | 135.7 (25.9) | 0.19 |
| HDL cholesterol (mg/dl) | 54.3 (15.3) | 55.7 (15.2) | 53.7 (15.3) | 44.9 (12.3) | <0.01 |
| LDL cholesterol (mg/dl) | 101.3 (31.5) | 104.0 (32.0) | 99.0 (30.5) | 96.0 (33.7) | <0.01 |
| Vitamin D25 (ng/ml) | 25.9 (10.4) | 24.8 (9.1) | 27.2 (11.5) | 25.1 (11.3) | <0.01 |
| C-reactive protein (mg/L)b | 2.0 (1.0, 4.5) | 1.8 (0.9, 4.1) | 2.1 (1.0, 5.0) | 3.0 (1.8, 7.8) | <0.01 |
| Creatinine (mg/dl) | 1.1 (0.5) | 0.8 (0.1) | 1.2 (0.2) | 2.7 (1.4) | <0.01 |
| Cystatin C (mg/L) | 1.2 (0.5) | 1.0 (0.2) | 1.3 (0.3) | 2.4 (1.0) | <0.01 |
| MDRD eGFR | 61.8 (19.1) | 77.0 (12.9) | 49.8 (8.2) | 23.7 (7.4) | <0.01 |
| CKD-Epi eGFR | 58.8 (17.0) | 72.9 (8.5) | 47.7 (8.1) | 21.9 (7.1) | <0.01 |
| Cystatin C eGFR using one- variable equation | 69.8 (21.7) | 82.6 (17.7) | 60.3 (15.9) | 31.2 (10.6) | <0.01 |
| Cystatin C eGFR using three- variable equation | 61.9 (19.2) | 73.4 (15.9) | 53.4 (13.7) | 28.3 (9.5) | <0.01 |
The data are presented either as means (SD) or percentages. Represent P = 0.0000 as P < 0.01.
a
Trend P values.
b
Median [IQR] with Kruskal-Wallis test.