Table 1.
Characteristics of the study participants
| All (n = 72) | Tertile of VBD |
P | |||
|---|---|---|---|---|---|
| VBD (77.6 to 162 HU) (n = 24) | VBD (168.5 to 210.1 HU) (n = 24) | VBD (212.2 to 292.8 HU) (n = 24) | |||
| Age (years) | 52 ± 11.7 | 55.7 ± 10.8 | 54.9 ± 8.9 | 45.9 ± 12.9 | 0.005 |
| Male (%) | 70 | 62.5 | 79.2 | 58.3 | 0.27 |
| CKD etiology (%) | |||||
| hypertension | 40 | 37.5 | 25 | 29 | |
| diabetes | 30 | 25 | 54.2 | 20.8 | |
| others | 30 | 37.5 | 20.8 | 50.2 | |
| Diabetes (%) | 42 | 41.7 | 41.7 | 41.7 | 1.00 |
| BMI (kg/m2) | 25.3 ± 4.5 | 26.4 ± 4.5 | 27 ± 5.2 | 25.7 ± 3.8 | 0.66 |
| Creatinine clearance (ml/min per 1.73 m2) | 40.4 ± 18.2 | 38.4 ± 18 | 40.7 ± 17 | 42.2 ± 20.2 | 0.78 |
| Proteinuria (g/24 h) | 0.22 (0 to 1.7) | 0.31 (0 to 1.03) | 0.14 (0 to 1.22) | 0.17 (0 to 1.18) | 0.85 |
| Hemoglobin (g/dl) | 13.1 ± 2.1 | 12.8 ± 1.9 | 13.1 ± 2.5 | 13.5 ± 1.8 | 0.51 |
| Glucose (mg/dl) | 100 (92 to 153.7) | 107 (96 to 164.7) | 102.5 (90.5 to 178.5) | 99.5 (84.5 to 133.5) | 0.68 |
| Total cholesterol (mg/dl) | 203 ± 44 | 204 ± 42 | 207 ± 44 | 199 ± 48 | 0.82 |
| HDL (mg/dl) | 49 ± 11.7 | 51 ± 12.8 | 50 ± 12.5 | 47.6 ± 9.7 | 0.58 |
| LDL (mg/dl) | 111 (93 to 134) | 106.5 (81 to 135.5) | 122 (96 to 135) | 111 (92 to 133.7) | 0.70 |
| Triglycerides (mg/dl) | 145 (101 to 202) | 161.5 (98 to 243) | 139.5 (110.7 to 230) | 124 (94 to 176.7) | 0.51 |
| CRP (mg/dl) | 0.41 (0.13 to 0.83) | 0.33 (0.13 to 0.54) | 0.46 (0.18 to 1.73) | 0.43 (0.1 to 0.69) | 0.79 |
| Bicarbonate (mEq/L) | 24 (21 to 26) | 24 (21.8 to 26) | 23.9 (22.4 to 27) | 24 (21.5 to 26) | 0.90 |
| Ionized calcium (mmol/L) | 1.30 ± 0.59 | 1.3 ± 0.05 | 1.31 ± 0.60 | 1.31 ± 0.66 | 0.70 |
| Phosphorus (mg/dl) | 3.7 ± 0.66 | 3.65 ± 0.72 | 3.7 ± 0.56 | 3.7 ± 0.66 | 0.92 |
| Alkaline phosphatase (U/L) | 118.5 (75 to 179.7) | 116 (95 to 171) | 120 (71 to 168.7) | 121.5 (67.5 to 211.7) | 0.85 |
| iPTH (pg/ml) | 103 (26 to 1028) | 111.5 (75 to 224.5) | 99.5 (65 to 132) | 97.5 (49.5 to 174.7) | 1.00 |
| 25(OH)D (ng/dl)a | 33.6 ± 1.66 | 33.6 ± 8 | 30.6 ± 14.8 | 36.7 ± 14.9 | 0.32 |
| Calcium score (AU) | 10.5 (0 to 120) | 85.7 (2.8 to 517.7) | 3.7 (0 to 78.1) | 0.55 (0 to 31.8) | 0.03 |
Results are presented as mean ± SD, median and interquartile range, or proportions. CRP, C-reactive protein; CKD, chronic kidney disease; HU, Hounsfield unit; VBD, vertebral bone density; BMI, body mass index; iPTH, intact parathyroid hormone; 25(OH)D, 25-hydroxyvitamin D; AU, Agatston unit.
a
n = 63.