Table 3.
Effect of HBV infection on overall graft survival, death-censored graft survival, and mortality in Cox regression analysis
Living Donor Transplant |
Deceased Donor Transplant |
|||
---|---|---|---|---|
Unadjusted HR | Adjusted HR | Unadjusted HR | Adjusted HR | |
Overall graft failure | 0.91 (0.71 to 1.15) | 0.90 (0.62 to 1.30) | 1.01 (0.88 to 1.17) | 1.10 (0.82 to 1.47) |
Death-censored graft failure | 0.95 (0.70 to 1.28) | 0.74 (0.45 to 1.24) | 0.98 (0.81 to 1.19) | 1.06 (0.85 to 1.33) |
Mortality | 0.88 (0.62 to 1.24) | 0.98 (0.59 to 1.63) | 0.99 (0.82 to 1.20) | 1.09 (0.88 to 1.36) |
Potential risk factors in the univariate analysis (P < 0.1) were selected into the multivariate analysis. Other analyzed covariates: recipient age, gender, body mass index, race, comorbid (diabetes, hypertension, cerebrovascular disease), dialysis duration, donor HBcAb, expanded criteria donor, HLA DR mismatch, cold ischemia time (in deceased donor), induction therapy, and immunosuppressants at discharge (tacrolimus, mycophenolate mofetil and enteric coated mycophenolate sodium, mammalian target of rapamycin inhibitors, or steroids).