Table 2.
Relative rates of mortality over 21 years by units of alcohol consumed a week. Figures are relative risks (95% confidence interval) adjusted for various factors
| Mortality and adjustment for relative risk | None | 1-7 | 8-14 | 15-21 | 22-34 | ⩾35 | P value for any drinking v none* | P value for trend consumption† |
|---|---|---|---|---|---|---|---|---|
| All cause | ||||||||
| No of deaths | 498 | 281 | 267 | 199 | 212 | 186 | ||
| Adjustment A | 1 | 1.00 (0.87 to 1.16) | 1.02 (0.88 to 1.18) | 1.34 (1.14 to 1.58) | 1.49 (1.27 to 1.75) | 1.74 (1.47 to 2.06) | 0.0003 | 0.0001 |
| Adjustment B | 1 | 1.03 (0.89 to 1.19) | 0.95 (0.81 to 1.10) | 1.12 (0.95 to 1.32) | 1.24 (1.05 to 1.46) | 1.33 (1.12 to 1.59) | 0.12 | 0.0006 |
| Adjustment C | 1 | 1.03 (0.89 to 1.20) | 0.93 (0.80 to 1.08) | 1.10 (0.93 to 1.29) | 1.22 (1.03 to 1.44) | 1.25 (1.05 to 1.50) | 0.22 | 0.006 |
| Coronary heart disease | ||||||||
| No of deaths | 198 | 122 | 91 | 79 | 72 | 63 | ||
| Adjustment A | 1 | 1.09 (0.87 to 1.37) | 0.87 (0.68 to 1.11) | 1.33 (1.02 to 1.72) | 1.26 (0.96 to 1.65) | 1.46 (1.10 to 1.94) | 0.15 | 0.010 |
| Adjustment B | 1 | 1.13 (0.90 to 1.42) | 0.81 (0.63 to 1.05) | 1.09 (0.83 to 1.42) | 1.04 (0.79 to 1.37) | 1.08 (0.80 to 1.45) | 0.86 | 0.99 |
| Adjustment C | 1 | 1.13 (0.90 to 1.42) | 0.79 (0.61 to 1.01) | 1.06 (0.81 to 1.38) | 1.01 (0.77 to 1.34) | 1.00 (0.75 to 1.35) | 0.91 | 0.69 |
| Stroke | ||||||||
| No of deaths | 38 | 20 | 21 | 19 | 18 | 17 | ||
| Adjustment A | 1 | 0.98 (0.57 to 1.69) | 1.13 (0.66 to 1.92) | 1.80 (1.04 to 3.12) | 1.81 (1.03 to 3.17) | 2.33 (1.31 to 4.14) | 0.07 | 0.0005 |
| Adjustment B | 1 | 0.98 (0.57 to 1.69) | 1.08 (0.63 to 1.85) | 1.53 (0.87 to 2.68) | 1.59 (0.89 to 2.82) | 1.98 (1.09 to 3.59) | 0.19 | 0.006 |
| Adjustment C | 1 | 0.96 (0.55 to 1.65) | 1.02 (0.59 to 1.75) | 1.46 (0.84 to 2.57) | 1.56 (0.88 to 2.79) | 1.67 (0.91 to 3.06) | 0.31 | 0.013 |
| Alcohol related causes | ||||||||
| No of deaths | 21 | 14 | 17 | 17 | 21 | 18 | ||
| Adjustment A | 1 | 1.15 (0.58 to 2.26) | 1.47 (0.78 to 2.80) | 2.60 (1.37 to 4.93) | 3.31 (1.81 to 6.07) | 3.72 (1.98 to 7.00) | 0.003 | 0.0001 |
| Adjustment B | 1 | 1.20 (0.61 to 2.37) | 1.39 (0.73 to 2.64) | 2.25 (1.18 to 4.31) | 2.78 (1.49 to 5.17) | 2.94 (1.52 to 5.68) | 0.012 | 0.013 |
With PROC PHREG with alcohol as categorical variable.
With PROC PHREG with units per week as continuous variable.
A=adjusted for age.
B=adjusted for age, smoking, cholesterol, body mass index, adjusted FEV1, social class (six social classes), father’s social class (six social classes), education, car use, siblings, deprivation category, angina, ischaemia on electrocardiogram, and bronchitis.
C=adjusted for age, smoking, cholesterol, body mass index, adjusted FEV1, social class (six social classes), father’s social class (six social classes), education, car use, siblings, deprivation category, angina, ischaemia on electrocardiogram, bronchitis, and diastolic blood pressure.