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. Author manuscript; available in PMC: 2011 Jun 7.
Published in final edited form as: Gene Ther. 2008 May 8;15(19):1311–1320. doi: 10.1038/gt.2008.78

Figure 2.

Figure 2

X-gal staining of the posterior segment (a) and Epon-embedded sections of mouse retinas transduced with the EIAV-CMV-LacZ vector (b) or the HIV-EF1α-LacZ vector (c). (a) A single injection of the EIAV-CMV-LacZ vector transduced ~20–30% of the entire retina. (b and c) Retinal sections of 18 days old mice, injected subretinally with 1 µl of viral solution containing 3–5 × 105 TU of either EIAV-CMV-LacZ (b) or HIV-EF1α-LacZ (c) 14 days earlier. EIAV-derived vector transduced ~5% of photoreceptors, retinal pigment epithelium (RPE) and occasionally Mueller cells (b), whereas transduction was restricted to RPE cells with the HIV-derived vector (c). Representative images of n = 10 eyes (a and b) and n = 6 eyes (c) are shown.