Table 1. Structure and Biochemical and Cell-Based Inhibition for SR-3306a.
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The biochemical IC50 values ± standard deviation are the average of 16 experiments for JNK3, 2 experiments for JNK2, 6 experiments for JNK1, 2 experiments for p38, and 6 experiments for the cell-based IC50 (p-c-jun inhibition). All enzymes used were human recombinant enzymes.