Table 2. The SWI/SNF family.
| Subfamily |
SWI/SNF |
||||||
|---|---|---|---|---|---|---|---|
| Species | Yeast | Yeast | Fly | Human | Mouse | Mouse | Mouse |
| Complex | SWI/SNF | RSC | BAP | BAF | esBAF | npBAF | nBAF |
| Swi2/Snf2 | Sth1 | BRM | BRG1/SMARCA4 or hBRM/SMARCA2 | BRG1/SMARCA4 | BRG1/SMARCA4 | BRG1/SMARCA4 | |
| OSA/eyelid or BAP170 | BAF250a/ARID1A or BAF250b/ARID1B or BAF200/ARID2* | BAF250a/ARID1A | BAF250a/ARID1A or BAF250b/ARID1B or BAF200/ARID2* | BAF250a/ARID1A or BAF250b/ARID1B or BAF200/ARID2* | |||
| Rsc1, Rsc2, Rsc4 | Polybromo | BAF180* | |||||
| Swi3 | Rsc8 | MOR/BAP155 | BAF155/SMARCC1 and/or BAF170/SMARCC2 | BAF155/SMARCC1 | BAF155/SMARCC1 and/or BAF170/SMARCC2 | BAF155/SMARCC1 and/or BAF170/SMARCC2 | |
| Swp73 | Rsc6 | BAP60 | BAF60a/SMARCD1 or BAF60b/SMARCD2 or BAF60c/SMARCD3 | BAF60a/SMARCD1 | BAF60a/SMARCD1 | BAF60a/SMARCD1 | |
| Arp7, Arp9 | Arp7, Arp9 | BAF55 or BAP47 | BAF53a or BAF53b | BAF53a | BAF53a | BAF53b | |
| Snf5 | Sfh1 | SNR1/BAP45 | BAF47/hSNF5/SMARCB1 | BAF47/SNF5/SMARCB1 | BAF47/SNF5/SMARCB1 | BAF47/SNF5/SMARCB1 | |
| SAYP | BAF45a or BAF45b or BAF45c or BAF45d | BAF45d | BAF45a or BAF45d | BAF45b or BAF45c or BAF45d | |||
| BAP111/dalao | BAF57/SMARCE1 | BAF57/SMARCE1 | BAF57/SMARCE1 | BAF57/SMARCE1 | |||
| β-actin | β-actin | β-actin | β-actin | β-actin | |||
| Unique Subunits | Swi1/Adr6, Swp82, Taf14, Snf6, Snf11 | Rsc3, 5, 7, 9, 10, 30, Htl1, Lbd7, Rtt102 | Brd7*, Brd9 |
*ARID2, BAF180, and Brd7 are proposed subunits of the PBAF complex. Despite coassociation with BRG1, these proteins are not dedicated subunits of the BAF complex as assessed by glycerol gradient centrifugation (121, Hargreaves DC and Crabtree GR, unpublished observations).