Skip to main content
. 2011 Jun 7;5(6):e1173. doi: 10.1371/journal.pntd.0001173

Table 1. Loci controlling survival after T. b. brucei infection - Single gene effect.

Marker Group Genotype P value corr. P value
CC CS SS
D3Mit45 females 15.88±0.36 (n = 18) 16.98±0.41 (n = 48) 19.58±0.93 (n = 19) 0.0010 0.0494
( Tbbr1 ) both sexes 15.17±0.35 (n = 39) 15.73±0.33 (n = 96) 17.22±0.40 (n = 34) 0.0077 NS (0.267)
D8Mit85 females 18.32±0.86 (n = 20) 15.99±0.38 (n = 44) 18.03±0.85 (n = 20) 0.0011 0.0542 (suggestive)
both sexes 16.98±0.40 (n = 43) 15.14±0.35 (n = 89) 15.99±0.37 (n = 36) 0.0024 NS (0.0994)
D12Mit37 females 19.23±0.90 (n = 15) 17.29±0.43 (n = 53) 15.89±0.36 (n = 15) 0.0004 0.0224
( Tbbr2 ) both sexes 17.06±0.40 (n = 32) 15.74±0.27 (n = 98) 15.38±0.35 (n = 37) 0.0013 0.0583 (suggestive)

F2 hybrids between CcS-11 and BALB/c were tested. Means and standard errors of means of survival times and P-values were computed by analysis of variance. Logarithmic (Log10) transformation was used to obtain normal distribution and the obtained values were retransformed after calculation. Number of tested mice is shown in brackets.