Table 1. Loci controlling survival after T. b. brucei infection - Single gene effect.
Marker | Group | Genotype | P value | corr. P value | |||||
CC | CS | SS | |||||||
D3Mit45 | females | 15.88±0.36 | (n = 18) | 16.98±0.41 | (n = 48) | 19.58±0.93 | (n = 19) | 0.0010 | 0.0494 |
( Tbbr1 ) | both sexes | 15.17±0.35 | (n = 39) | 15.73±0.33 | (n = 96) | 17.22±0.40 | (n = 34) | 0.0077 | NS (0.267) |
D8Mit85 | females | 18.32±0.86 | (n = 20) | 15.99±0.38 | (n = 44) | 18.03±0.85 | (n = 20) | 0.0011 | 0.0542 (suggestive) |
both sexes | 16.98±0.40 | (n = 43) | 15.14±0.35 | (n = 89) | 15.99±0.37 | (n = 36) | 0.0024 | NS (0.0994) | |
D12Mit37 | females | 19.23±0.90 | (n = 15) | 17.29±0.43 | (n = 53) | 15.89±0.36 | (n = 15) | 0.0004 | 0.0224 |
( Tbbr2 ) | both sexes | 17.06±0.40 | (n = 32) | 15.74±0.27 | (n = 98) | 15.38±0.35 | (n = 37) | 0.0013 | 0.0583 (suggestive) |
F2 hybrids between CcS-11 and BALB/c were tested. Means and standard errors of means of survival times and P-values were computed by analysis of variance. Logarithmic (Log10) transformation was used to obtain normal distribution and the obtained values were retransformed after calculation. Number of tested mice is shown in brackets.