Figure 2.
Cumulative incidence of recurrence rates by tumor site and DNA mismatch repair (MMR) status in stage III colon cancer patients treated in adjuvant chemotherapy trials. A) Effect of 5-fluorouracil (FU)-based adjuvant therapy (treated) vs surgery alone or no 5-FU (untreated) by site of tumor recurrence in patients with deficient MMR colon cancers. B) Effect of 5-FU-based adjuvant therapy (treated) vs surgery alone or no 5-FU (untreated) by site of tumor recurrence in patients with proficient MMR colon cancers. P values were calculated using a two-sided χ2 test at 5 years.