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. 2011 May 19;103(11):863–875. doi: 10.1093/jnci/djr153

Figure 3.

Figure 3

Effect of 5-fluorouracil (FU)-based adjuvant therapy on disease-free survival (DFS) in colon cancer patients with suspected germline mutations vs sporadic tumors. A) Effect of 5-FU-based therapy on DFS in colon cancer patients with suspected germline mutations. DFS rates with 95% confidence intervals (dotted lines) are shown in patients who received 5-FU-based treatment (blue) vs observation or no 5-FU (red). B) Effect of 5-FU-based therapy on DFS in patients with suspected sporadic colon cancer. DFS rate and 95% confidence intervals (dotted lines) are shown in patients who received 5-FU-based treatment (blue) vs observation or no 5-FU (red). P values were calculated using a two-sided likelihood ratio test after adjustment for stage, age, and sex. Obs = Observation.